Temozolomide 20 mg is an oral anticancer drug containing temozolomide. Temozolomide belongs to a group of drugs called alkylating agents (imidazotetrazines, specifically), which are used in oncology to treat Temozolomide 20mg capsule certain forms of malignant brain tumors.
Temozolomide 20mg capsule in pakistan is a pro-drug. After ingestion into the body, it spontaneously converts to the active substance (MTIC). The active substance damages the DNA of proliferating cells (methylation), thereby stopping replication of genetic material of cancer cells. This slows down or stops the growth and development of the tumor, resulting in cancer cell death.
Glioblastoma Multiforme (GBM): Malignant brain tumor. Usually, the drug is first used in conjunction with radiotherapy (concomitant period), and later the treatment is continued alone.
Anaplastic Astrocytoma: Malignant brain tumor. The drug is prescribed to those patients who have a recently diagnosed tumor or the one that came back/developed further after treatment.
Method of administration: Capsules need to be taken orally intact with a full glass of water. Never chew, crush, cut, or open the capsule because it is dangerous to inhale or touch its content.
Dosage regimen: It is strongly recommended to take the drug on an empty stomach (one hour before food intake or three hours after) or before going
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