Description
METREX (METH oh TREX ate) treats inflammatory conditions such as arthritis and psoriasis. It works by decreasing inflammation, which can reduce pain and prevent long-term injury to the joints and skin. It may also be used to treat some types of cancer. It works by slowing down the growth of cancer cells.
METREX tablet is used alone or together with other medicines to treat several types of cancer, such as breast, head and neck, lung, blood (eg, acute lymphoblastic leukemia or ALL), bone, lymph node (eg, mycosis fungoides, relapsed or refractory non-Hodgkin lymphoma), or uterus cancer.
The drug is now most commonly used for the maintenance of induced remissions. Trexate tablets are also effective in the treatment of the advanced states (III and IV, Peters Staging System) of lymphosarcoma, particularly in children and in advanced cases of mycosis fungoides
Methotrexate is indicated in the treatment of gestational choriocarcinoma, chorio adenoma destruens and hydatidiform mole. Methotrexate is used in maintenance therapy in combination with other chemotherapeutic agents.
The most common side effects are fatigue a day or two after you take methotrexate, which is why I suggest taking it at night,” he says. “Also gastrointestinal issues. Your stool may be loose, or you may feel queasy or nauseated for a day or two after.
Methotrexate is in a class of medications called antimetabolites. Methotrexate treats cancer by slowing the growth of cancer cells. Methotrexate treats psoriasis by slowing the growth of skin cells to stop scales from forming. Methotrexate may treat rheumatoid arthritis by decreasing the activity of the immune system.
GI problems such as nausea and vomiting are the most common side effects associated with methotrexate, affecting between 20% and 65% of rheumatoid arthritis (RA) patients who take the drug. Up to one-third develop mouth ulcers or sores. Many also complain of headaches, fatigue and an overall “blah” feeling.
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