Methadone 20mg are a synthetic opioid agonist used in the treatment of severe chronic pain and Opioid Use Disorder (OUD).
Classification: Controlled substance under METHADONE 20MG TABLET Schedule II and an opioid analgesic.
Mechanism of action: Acts as a full agonist at U-opioid receptors, N MDA receptor METHADONE 20MG TABLET IN PAKISTAN antagonist and inhibitor of re uptake of serotonin and nor epinephrine.
Duration: Has a long half-life (approximately 24 hours) allowing prolonged METHADONE 20MG TABLET PRICE IN PAKISTAN action although the effect on pain relief is shorter than the body clearance.
Severe Chronic Pain: Used in the treatment of chronic pain which is difficult to control and requires continuous opioid therapy, around the clock, and for which other methods or agents have failed.
OUD: Used as part of medical program to prevent withdrawals and cravings but does not cause euphoria like short-acting narcotics when correctly used.
Life-Threatening Complications: Causes life-threatening, life-altering and even fatal respiratory depression, profound sedation, coma, and accidental ingestion risk (especially fatal in children).
Boxed Warning: Has serious risk of abuse, addiction, misuse; combination with benzo diazepines or CNS depressants can cause fatal overdose.
Adverse Reactions: Constipation, nausea, vomiting, dizziness, somnolence, dry mouth, and sweating.
Methadone is a dipheny lheptane derivative synthetic opioid and medically classified as a narcotic / opioid analgesic
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