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Description

Formulation: Powder for Oral Suspension
Strength: 4g per sachet

Description:
Questran (cholestyramine) is a medication used primarily for managing high cholesterol levels and certain types of diarrhea. It works by binding to bile acids in the intestines, preventing their reabsorption and reducing the amount of cholesterol in the bloodstream. The active ingredient in Questran is cholestyramine, which is a bile acid sequestrant.

Questran comes in the form of a powder that is mixed with water to form a suspension. The powder is typically packaged in individual 4g sachets, making it easy to measure and administer. This form allows for flexible dosing depending on the patient’s condition.

Uses:

Hyperlipidemia (High Cholesterol): Questran helps to lower levels of low-density lipoprotein (LDL) cholesterol by binding bile acids in the intestine.
Bile Acid Diarrhea: It can be used to treat diarrhea caused by excess bile acids in the gastrointestinal tract.
Pruritus Associated with Biliary Obstruction: Questran is also used to alleviate itching caused by liver disease or bile duct obstruction.
Mechanism of Action:
Cholestyramine binds bile acids in the intestines, which are then excreted rather than being reabsorbed into the bloodstream. This helps to lower cholesterol levels and prevent diarrhea caused by bile acid malabsorption.

Dosage:

Typically, the recommended dose starts at 4g per day.
The dose may be gradually increased based on the patient’s condition and response to the treatment.
Questran should be taken mixed with water or non-carbonated beverages for ease of consumption.
Key Points:

Active Ingredient: Cholestyramine
Strength: 4g per sachet
Form: Powder for Oral Suspension
Administration: Oral, mixed with water or non-carbonated drinks
Uses: High cholesterol, bile acid diarrhea, pruritus from biliary obstruction
Precautions: Can interact with certain medications, and should be taken at least 1 hour before or 4-6 hours after other medications.
Side Effects:
Common side effects include constipation, abdominal discomfort, and bloating. In rare cases, it can lead to more severe gastrointestinal issues.

Storage:
Store in a cool, dry place away from direct sunlight. Keep out of the reach of children.

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